ICI-118551 HCl|72795-01-8 (HCl salt); 72795-19-8 (free base).--Shanghai xingMo Biotechnology

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Description

ICI-118551, also known as ICI-118,551, is a selective beta-2 (β2) adrenergic receptor antagonist. ICI-118551 binds to the β2 subtype with at least 100 times greater affinity than β1 or β3, the two other known subtypes of the beta adrenoceptor. The compound was developed by Imperial Chemical Industries, which was acquired by AkzoNobel in 2008. ICI-118,551 has no known therapeutic use in humans although it has been used widely in research to understand the action of the β2 adrenergic receptor, as few other specific antagonists for this receptor are known.

Chemical Structure

Chemical Name

(2R,3S)-3-(isopropylamino)-1-((7-methyl-2,3-dihydro-1H-inden-4-yl)oxy)butan-2-ol hydrochloride

SMILES Code

C[C@H](NC(C)C)[C@@H](O)COC1=CC=C(C)C2=C1CCC2.[H]Cl

Theoretical Analysis

XingMo Cat#:XM020
Product Name:ICI-118551 HCl
Synonyms:ICI118551; ICI118551; ICI 118551; ICI118551; ICI118551; ICI 118551.
CAS#:72795-01-8 (HCl salt); 72795-19-8 (free base).
Chemical Formula:C₁₇H₂₈ClNO₂
Exact Mass:313.87
Molecular Weight:313.87
Purity:>98%

Technical Data

Appearance: white to off-white solid powder

Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0-4℃ for short term (days to weeks) or -20℃ for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

WARNING: This product is for research use only, not for human or veterinary use

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