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| Description |
| FT-4101 is a potent, selective, oral small molecule inhibitor of fatty acid synthase (FASN), a key enzyme in the de novo lipogenesis (DNL) pathway responsible for hepatic lipid composition. Through FASN inhibition, FT-4101 is expected to reduce the rate of new fat production, thereby systemically affecting lipid accumulation in the liver and potentially mitigating the cellular damage, inflammation, and fibrosis that characterizes the pathology of nonalcoholic steatohepatitis (NASH). FT-4101 is being evaluated in a randomized, double-blind, placebo-controlled Phase 2 study to evaluate the safety, tolerability, pharmacokinetics/pharmacodynamics (PK/PD) and efficacy of FT-4101 in adult patients with NASH. |
| Chemical Name |
| (4-(2-fluoro-4-(1-methyl-1H-benzo[d]imidazol-5-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone |
| Theoretical Analysis |
XingMo Cat#:XM798
Product Name:FT-4101
Synonyms:FT-4101,FT4101
CAS#:2230273-76-2
Chemical Formula:C23H23FN4O3
Molecular Weight:422.459
Purity:98%
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| Technical Data |
Solubility: Soluble in DMSO, not in water
Shelf Life:
>2 years if stored properly.
Drug Formulation:
This drug may be formulated in DMSO
Stock Solution Storage:
0 - 4 ℃ for short term (days to weeks), or -20 ℃ for long term (months). |
WARNING: This product is for research use only, not for human or veterinary use
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